- 54-mile march from Selma to Montgomery
- A fantastic meteor shower causes this night to be known as "the night stars fell on Alabama."
- Alabama Coal Mining Company begins first systematic underground mining in the state near Montevallo.
- Alabama Insane Hospital established at Tuscaloosa;
- Alabama Public School Act creates first state-wide education system by providing funding for schools
- Alabama School for the Deaf founded in Talladega;
- Alabama Senator Hugo Black appointed by President Franklin Roosevelt to the U.S. Supreme Court.
- Alabama Territory is created
- Alabama formally adopts a state flag
- Alabama gold rush
- Alabama's 167th Regiment, a part of the 42nd "Rainbow Division," serves at the front longer than any U.S. regiment.
- Alabama's Constitution of 1875 is ratified
- Alabama's Heather Whitestone serves as first Miss America with a disability.
- Alabama's first railroad, the Tuscumbia Railway
- Area's first steamboat, constructed in St. Stephens.
- Army Ballistic Missile Agency established at Huntsville's Redstone Arsenal.
- Battle of Hobdy's Bridge last Indian battle in Alabama
- Battle of Mobile Bay
- Bell Factory (Madison County), state's first textile mill, chartered by legislature.
- Birmingham bombings of Civil Rights-related targets
- Birmingham native Condoleezza Rice is appointed National Security Advisor to President George W. Bush
- Birmingham was founded on June 1, 1871
- Boll Weevil, insect destroyer of cotton, enters state from Mississippi border.
- Booker T. Washington speech to Atlanta Cotton States and International Exposition urges racial accommodation
- Cahaba designated by the territorial legislature as Alabama's state capital.
- Capital moved to Tuscaloosa.
- Cedar Creek Furnace, the state's first blast furnace and commerical pig-iron producer
- Center of the American Civil Rights Movement
- Compromise of 1850
- Constitutional Convention meets in Huntsville and adopts state constitution.
- Convict lease system ended in Alabama.
- Creek Indian War, a part of the War of 1812, fought largely within the boundaries of present-day Alabama
- Daniel Pratt establishes cotton gin factory north of Montgomery
- Dr. James Marion Sims, "the Father of Modern Gynecology," establishes medical practice in Mt. Meigs
- East Alabama Male College established at Auburn by Methodists; evolved into Auburn University.
- First African-American flying unit in the U.S. military were trained in Alabama
- First African-American male with a weekly network television series
- First legislature of the Alabama Territory convenes at the Douglass Hote
- First state to declare Christmas a legal holiday
- Flowers is the first African American to win a gold medal in a winter olympics.
- Football and baseball star, Vincent Edward "Bo" Jackson was born in Bessemer. Jackson won the Heisman Trophy in 1985 and was the first professional athlete to be named an all star in two major sports.
- General Richard Taylor surrenders last sizable Confederate force at Citronelle, Mobile County
- German steel manufacturer ThyssenKrupp AG announces it will invest nearly $4 billion in plant construction in Mobile County
- Harper Lee of Monroeville wins the Pulitzer Prize for To Kill A Mockingbird
- Helen Keller is born in Tuscumbia
- Huntsville Normal and Industrial School chartered
- Huntsville-built "Jupiter" rocket places American satellite in orbit around Earth.
- Hyundai broke ground in Montgomery, Alabama for its first U.S. automobile assembly plant
- Indian Removal Act
- James Rapier of Lauderdale County elected to U.S. Congress, one of three African American congressmen elected from Alabama during Reconstruction
- January 11, 1861, the State of Alabama adopted the ordinances of secession
- Joined the union as the 22nd state in 1819
- Judson Female Institute, a Baptist college, opens in Marion;
- Kathryn Thornton, a native of Montgomery and graduate of Auburn University, becomes the first woman to fly on a military space mission on the Space Shuttle Discovery.
- LaGrange College chartered by legislature
- Lawrence County native Jesse Owens wins his first gold medal at the 1936 Olympics in Berlin
- Le Moyne brothers, Iberville and Bienville, establish French fort and settlement, Fort Louis de la Mobile
- Legislature charters Athens Female Academy, which later becomes Athens State University.
- Legislature elects William Rufus King and John W. Walker as Alabama's first U.S. senators.
- Legislature selects Montgomery as new capital;
- Lurleen Wallace inaugurated as state's first woman governor
- Martin Luther King Jr, of Atlanta is installed as minister of Dexter Avenue Baptist Church in Montgomery
- Martin Luther King Jr.'s "Letter from Birmingham Jail" is issued to the public
- Montgomery Bus Boycott
- Montgomery, was the Confederacy's first capital
- National Baptist Convention (African-American Baptists) organized at Montgomery
- Newspapers established in Mobile and Huntsville
- Nine black youths, soon to be known as the Scottsboro Boys, are arrested in Paint Rock and jailed in Scottsboro
- On the thirtieth anniversary of statehood the capitol in Montgomery is destroyed by fire.
- Oscar Adams was elected to the Alabama Supreme Court, becoming the first African American elected to statewide constitutional office in Alabama.
- Played a key role in the American Civil War
- President George W. Bush awards To Kill A Mockingbird author Harper Lee the Presidential Medal of Freedom, the nation's highest civilian award
- President Monroe signs the Alabama enabling act.
- Rousseau's Raid through north and east-central Alabama
- Schools established at St. Stephens and Huntsville
- Sculptor Guiseppe Moretti created an iron statue of Vulcan
- Spanish capture Mobile during American Revolution
- Spanish surrender Mobile to American forces
- State prison established by legislature; first convict incarcerated in 1842
- Streight's Raid in north Alabama
- Talladega Speedway opens with its first running of the Talladega 500
- Tens of thousands of African Americans migrated north from Alabama in the Great Migration
- Territorial governor William Wyatt Bibb is elected the state's first governor
- The Alabama Girls' Industrial School opens its doors as the first state-supported industrial and technical school devoted to training girls to make a living.
- The Alabama Shakespeare Festival began as a summer stock program in Anniston
- The Alabama Space and Rocket Center in Huntsville is dedicated
- The Alabama Supreme Court, composed of Alabama's circuit court judges, convenes for the first time.
- The Civil War begins when Confederates fire at Fort Sumter in Charleston Harbor, acting upon instructions telegraphed from Montgomery
- The Dixiecrat Convention assembles in Birmingham, with over 6,000 delegates from across the South in attendance
- The Freedom Riders arrive at the Greyhound bus terminal in Montgomery where they are attacked by an angry mob
- The State of Alabama granted Hunt Oil Company a permit to drill the A.R. Jackson Well No. 1 near Gilbertown
- The first Auburn/Alabama football game is played in Birmingham's Lakeview Park
- The first southern team to be honored with an invitation to the Rose Bowl
- The steamboat Harriet reaches Montgomery after ten days of travel from Mobile
- U.S. Army Lieutenant John McClary takes possession of Fort St. Stephens from the Spanish, and the United States flag is raised for the first time on soil that would eventually belong to Alabama
- University of Alabama formally opens its doors.
- Until 1832, there was only one party in the state
- Vivian Malone and James Hood register for classes as first African-American students.
- Wilson's Raid through north and central Alabama
- Wright Brothers, Orville and Wilbur, establish "flying school" on land outside Montgomery
jds